|
Symbol Name ID |
Gpx1
glutathione peroxidase 1 MGI:104887 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Gastrointestinal hemorrhage |
Retinal hemorrhage |
Cerebral hemorrhage |
Bruising susceptibility |
Reduced alpha/beta synthesis ratio |
Persistence of hemoglobin F |
Increased mean corpuscular volume |
Reticulocytosis |
Anemia |
Hemolytic anemia |
Chronic hemolytic anemia |
Increased red cell sickling tendency |
Hypochromic anemia |
Hypochromic microcytic anemia |
Iron deficiency anemia |
Microcytic anemia |
Target cells |
Leukocytosis |
Acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Acute myeloid leukemia |
Abnormality of thrombocytes |
Thrombocytosis |
Lymphoma |
Multiple myeloma |
Abnormality of the spleen |
Splenic infarction |
Splenomegaly |
| Disease(s) Associated with GPX1 | ||||||||||||||||||||||||||||||||
| acute lymphoblastic leukemia | ||||||||||||||||||||||||||||||||
| acute myeloid leukemia | ||||||||||||||||||||||||||||||||
| alpha thalassemia | ||||||||||||||||||||||||||||||||
| multiple myeloma | ||||||||||||||||||||||||||||||||
| non-Hodgkin lymphoma | ||||||||||||||||||||||||||||||||
| pseudoxanthoma elasticum | ||||||||||||||||||||||||||||||||
| sickle cell anemia |
| Mouse Phenotypes | abnormal platelet physiology |
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| Availability | Mouse Genotype | |
| Gpx1tm1Ysh/Gpx1tm1Ysh | ||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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